Institution name and department

KU Leuven, Department of Chemistry

Position held


Full professor



Celestijnenlaan 200F

3001 Leuven (Belgium)



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Key words 


Multicomponent reactions

Supramolecular chemistry





Medicinal chemistry



Areas of Research/Expertise 

 The Dehaen research groups has in the past years mainly been concerned with synthetic methodology in heterocyclic and medicinal chemistry, and in the synthesis and applications of different materials related to supramolecular chemistry, including macrocycles, electroactive materials and fluorescent dyes and sensors.

5 Most representative publications related to mechanochemistry 

R. Vroemans, Y. Verhaegen, M. T. T. Dieu, W. Dehaen, “Assembly of fully substituted triazolochromenes via a novel multicomponent reaction and mechanochemical synthesis” Beilstein J. Org. Chem. 2018, 14, 2689–2697. 

5 Most representative publications non-related to Mechanochemistry

1. S. Van De Vyver, J. Thomas, J. Geboers, S. Keyzer, M. Smet, W. Dehaen, P. A. Jacobs,  B. F. Sels, “Catalytic production of levulinic acid from cellulose and other biomass-derived carbohydrates with sulfonated hyperbranched poly(arylene oxindole)s” , Energy & Environm. Sci., 2011,  4, 3601-3610.

2. Boens, N.; Leen, V., Dehaen W.  Fluorescent indicators based on BODIPY, Chem. Soc. Rev. 2012, 41, 1130-1172.

3. Thomas, J.; John, J.; Parekh, N.; Dehaen, W. A Metal-​Free Three-​Component Reaction for the Regioselective Synthesis of 1,​4,​5-​Trisubstituted 1,​2,​3-​Triazoles Angew. Chem. Int. Ed. 2014, 53, 9964

4. Verbelen, B.; Boodts, S.; Hofkens, J.; Boens, N.; Dehaen, W. “Radical C-H arylation of the BODIPY core with aryldiazonium salts : synthesis of highly fluorescent red-shifted dyes”, Angew. Chem. Int. Ed. 2015, 54, 4612-4616

5. Thomas, J.; Jana, S.; John, J.; Liekens, S.; Dehaen, W. “A general metal-free route towards the synthesis of 1,2,3-triazoles from readily available primary amines and ketones” Chem. Commun. 2016, 52, 2885-2888.


Orcid ID/ Google Scholar/ Researchgate/ Scopus profiles

Orcid ID


Google Scholar




Scopus profiles


Twitter/ Linkedin/ Instagram accounts





Instagram accounts


Primary focus in mechanochemical research 


Contact Info

  • Université de Montpellier & Institut Charles Gerhardt de Montpellier (UMR 5253)
    c/o 8, Rue de l’Ecole Normale
    34296 Montpellier, Cedex 5 (France)

  • +33 (0)4 67 14 43 10
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COST Overview


EU COST is supported by the EU Framework Programme Horizon 2020.



COST Action CA18112