Institution name and department

Comenius University in Bratislava, Faculty of Natural Sciences, Department of Organic Chemistry

Position held


Professor of organic chemistry



Mlynska dolina, Ilkovičova 6, 842 15 Bratislava, Slovakia



This email address is being protected from spambots. You need JavaScript enabled to view it.

Key words 


Areas of Research/Expertise

Stereoseelctive synthesis and asymmetric catalysis; transition metal catalysis and organometallic coumpounds; domino reactions; sustainable chemistry; mechanochemistry; asymmetric organocatalysis.

5 Most representative publications related to mechanochemistry

1.    Organocatalyst efficiency in α-aminoxylation and α-hydrazination of carbonyl derivatives in aqueous media and ball-mill. Veverková, E.; Modrocká, V.; Šebesta, R. Eur. J. Org. Chem. 2017, 1191-1195. (

2.    Higher enantioselectivities in thiourea-catalyzed Michael additions under solvent-free Conditions. Šebesta, R.; Hestericová, M. Tetrahedron, 2014, 70, 901-905. (

3.    Organocatalyst Efficiency in the Michael Additions of Aldehydes to Nitroalkenes in Water and in a Ball-Mill. Veverková, E.; Poláčková, V.; Liptáková, L.; Kázmerová, E.; Mečiarová, M.; Toma, Š.; Šebesta, R. ChemCatChem 2012, 4, 1013-1018. (

5 Most representative publications non-related to Mechanochemistry 

1.  Trapping of chiral enolates generated by Lewis acid promoted conjugate addition of Grignard reagents to unreactive Michael acceptors by various electrophiles. Vargová,  D.; Perez,  J. M.; Harutyunyan, S. R.; Šebesta, R. Chem. Commun. 2019, 55, 11766-11769. (!divAbstract)

2.  Diastereoselective Pd-Catalyzed CH Arylation of Ferrocenylmethanamines with Arylboronic Acids or Pinacol Esters. Plevová, K.; Mudráková, B.; Rakovský, E.; Šebesta, R. J. Org. Chem. 2019, 84, 7312-7319. (

3.  Retro-Brook Rearrangement of Ferrocene-Derived Silyl Ethers. Bariak, V.; Malastová, A.; Almássy, A.; Šebesta, R. Chem. Eur. J. 2015, 21, 13445-13453. (

4.  Asymmetric one-pot conjugate addition of Grignard reagents to α,β-unsaturated compounds followed by reaction with carbenium ions. Drusan, M.; Rakovský, E.; Marek, J.; Šebesta, R. Adv. Synth. Catal. 2015, 357, 1493-1498. (

5.  Enantioselective Michael reaction of acetals with nitroalkenes – an improvement of the oseltamivir synthesis. Tisovský, P.; Peňaška, T.; Mečiarová, M.; Šebesta, R. ACS Sust. Chem. Eng. 2015, 3, 3429-3434. (

Orcid ID/ Google Scholar/ Researchgate/ Scopus profiles

Orcid ID


Google Scholar




Scopus profiles


Twitter/ Linkedin/ Instagram accounts





Instagram accounts


Primary focus in mechanochemical research

stereoselective reactions


Contact Info

  • Université de Montpellier & Institut Charles Gerhardt de Montpellier (UMR 5253)
    c/o 8, Rue de l’Ecole Normale
    34296 Montpellier, Cedex 5 (France)

  • +33 (0)4 67 14 43 10
  • This email address is being protected from spambots. You need JavaScript enabled to view it.

COST Overview


EU COST is supported by the EU Framework Programme Horizon 2020.



COST Action CA18112