Name   

Surname  

Liliana

Mazur

Institution name and department  

Institute of Chemical Sciences

Faculty of Chemistry

Maria Curie-Sklodowska University

Position held

lecturer

Address/Country

pl. Marii Curie-Skłodowskiej 2

20-031 Lublin

Poland

E-mail

Webpage

This email address is being protected from spambots. You need JavaScript enabled to view it.

https://www.umcs.pl/pl/addres-book-employee,1756,pl.html

Key word

crystal engineering

co-crystals

crystallography

hydrazones

polymorphs

Areas of Research/Expertise

X-ray crystallography and crystal engineering:

-        X-ray single crystal diffraction studies of small molecule organic and organometallic compounds,

-        molecular structure and intermolecular interactions in the solid state - identification of the molecular binding sites, main supramolecular synthons, the role of weak hydrogen bonds in stabilization of the crystal structure,

-        polymorph screening and preparation of polymorphic samples,

-        thermal stability studies, estimating of thermodynamic stability relationship of polymorphs (DSC, VT PXRD, DFT calculations),

-        mechanochemical preparation of adducts (molecular salts and co-crystals) of hydrazones with polycarboxylic acids,

-        polymorphism of multi-component crystal forms of APIs and salt-cocrystal equilibrium.

Chemical  synthesis:

-        synthesis of hydrazones, amidrazones, 1,2,4-triazoles and their transition metal complexes (a potential antibacterial and/or anticancer drugs)

-        synthesis of lanthanide coordination polymers with heteroaromatic polycarboxylic acids

Most representative publications related to mechanochemistry 

Mazur, L., Materek, I., Bond, A. D., Jones, W. Multicomponent crystal forms of a biologically active hydrazone with some dicarboxylic acids: Salts or cocrystals? Cryst. Growth Des. 2019, 5, 2663. https://doi.org/10.1021/acs.cgd.8b01795

5 Most representative publications non-related to Mechanochemistry 

1. Mazur, L., Sączewski, J., Jarzembska, K., Szwarc-Karabyka, K., Paprocka, R., Modzelewska-Banachiewicz, B. Synthesis, structural characterization and reactivity of new trisubstituted N¹-acylamidrazones: solid state and solution studies. CrystEngComm  2018, 20, 4179. https://doi.org/10.1039/c8ce00701b

2. Mazur, L., Kozioł, A. E., Jarzembska, K. N., Paprocka, R., Modzelewska-Banachiewicz, B. Polymorphism and isostructurality of the series of 3-(4 ,5-diaryl-4H-1,2,4-triazole-3-yl)propenoic acid derivatives. Cryst. Growth Des. 2017, 17, 2104. https://doi.org/10.1021/acs.cgd.7b00080

3. Mazur, L., Jarzembska, K. N., Kaminski, R., Hoser, A. A., Madsen, A. Ø., Pindelska, E., Zielińska-Pisklak, M. Crystal structures and thermodynamic properties of polymorphs and hydrates of selected 2‑pyridinecarboxaldehyde hydrazones. Cryst. Growth Des. 2016, 16, 3101. https://doi.org/10.1021/acs.cgd.5b01673

4. Mazur, L., Jarzembska, K., Kaminski, R., Wozniak, K., Pindelska, E., Zielinska-Pisklak, M. Substituent and solvent effects on intermolecular interactions in crystals of N-acylhydrazone derivatives: single-crystal X-ray, solid-state NMR and computational studies. Cryst. Growth Des. 2014, 14, 2263. https://doi.org/10.1021/cg401866x

5. Mazur, L., Modzelewska-Banachiewicz, B., Paprocka, R., Zimecki, M., Wawrzyniak, U. E., Kutkowska, J., Ziółkowska, G. Synthesis, crystal structure and biological activities of a novel amidrazone derivative and its copper(II) complex – A potential antitumor drug. J. Inorg. Biochem. 2012, 114, 55. https://doi.org/10.1016/j.jinorgbio.2012.04.021

Orcid ID/ Google Scholar/ Researchgate/ Scopus profiles

Orcid ID

0000-0001-8283-3484

Google Scholar

Researchgate

www.researchgate.net/profile/Liliana_Mazur

Scopus profiles

https://www.mendeley.com/profiles/liliana-mazur/

Twitter/ Linkedin/ Instagram accounts

Twitter/

Linkedin

https://www.linkedin.com/in/liliana-mazur-96a57652/

Instagram accounts

Primary focus in mechanochemical research