Name |
Surname |
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Liliana |
Mazur |
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Institution name and department |
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Institute of Chemical Sciences Faculty of Chemistry Maria Curie-Sklodowska University |
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Position held |
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lecturer |
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Address/Country |
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pl. Marii Curie-Skłodowskiej 2 20-031 Lublin Poland |
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Webpage |
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This email address is being protected from spambots. You need JavaScript enabled to view it. |
https://www.umcs.pl/pl/addres-book-employee,1756,pl.html |
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Key word |
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crystal engineering |
co-crystals |
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crystallography |
hydrazones |
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polymorphs |
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Areas of Research/Expertise |
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X-ray crystallography and crystal engineering:
- X-ray single crystal diffraction studies of small molecule organic and organometallic compounds, - molecular structure and intermolecular interactions in the solid state - identification of the molecular binding sites, main supramolecular synthons, the role of weak hydrogen bonds in stabilization of the crystal structure, - polymorph screening and preparation of polymorphic samples, - thermal stability studies, estimating of thermodynamic stability relationship of polymorphs (DSC, VT PXRD, DFT calculations), - mechanochemical preparation of adducts (molecular salts and co-crystals) of hydrazones with polycarboxylic acids, - polymorphism of multi-component crystal forms of APIs and salt-cocrystal equilibrium.
Chemical synthesis:
- synthesis of hydrazones, amidrazones, 1,2,4-triazoles and their transition metal complexes (a potential antibacterial and/or anticancer drugs) - synthesis of lanthanide coordination polymers with heteroaromatic polycarboxylic acids
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Most representative publications related to mechanochemistry |
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Mazur, L., Materek, I., Bond, A. D., Jones, W. Multicomponent crystal forms of a biologically active hydrazone with some dicarboxylic acids: Salts or cocrystals? Cryst. Growth Des. 2019, 5, 2663. https://doi.org/10.1021/acs.cgd.8b01795 |
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5 Most representative publications non-related to Mechanochemistry |
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1. Mazur, L., Sączewski, J., Jarzembska, K., Szwarc-Karabyka, K., Paprocka, R., Modzelewska-Banachiewicz, B. Synthesis, structural characterization and reactivity of new trisubstituted N1-acylamidrazones: solid state and solution studies. CrystEngComm 2018, 20, 4179. https://doi.org/10.1039/c8ce00701b 2. Mazur, L., Kozioł, A. E., Jarzembska, K. N., Paprocka, R., Modzelewska-Banachiewicz, B. Polymorphism and isostructurality of the series of 3-(4 ,5-diaryl-4H-1,2,4-triazole-3-yl)propenoic acid derivatives. Cryst. Growth Des. 2017, 17, 2104. https://doi.org/10.1021/acs.cgd.7b00080 3. Mazur, L., Jarzembska, K. N., Kaminski, R., Hoser, A. A., Madsen, A. Ø., Pindelska, E., Zielińska-Pisklak, M. Crystal structures and thermodynamic properties of polymorphs and hydrates of selected 2‑pyridinecarboxaldehyde hydrazones. Cryst. Growth Des. 2016, 16, 3101. https://doi.org/10.1021/acs.cgd.5b01673 4. Mazur, L., Jarzembska, K., Kaminski, R., Wozniak, K., Pindelska, E., Zielinska-Pisklak, M. Substituent and solvent effects on intermolecular interactions in crystals of N-acylhydrazone derivatives: single-crystal X-ray, solid-state NMR and computational studies. Cryst. Growth Des. 2014, 14, 2263. https://doi.org/10.1021/cg401866x 5. Mazur, L., Modzelewska-Banachiewicz, B., Paprocka, R., Zimecki, M., Wawrzyniak, U. E., Kutkowska, J., Ziółkowska, G. Synthesis, crystal structure and biological activities of a novel amidrazone derivative and its copper(II) complex – A potential antitumor drug. J. Inorg. Biochem. 2012, 114, 55. https://doi.org/10.1016/j.jinorgbio.2012.04.021
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Orcid ID/ Google Scholar/ Researchgate/ Scopus profiles |
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Orcid ID |
0000-0001-8283-3484 |
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Google Scholar |
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Researchgate |
www.researchgate.net/profile/Liliana_Mazur |
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Scopus profiles |
https://www.mendeley.com/profiles/liliana-mazur/ |
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Twitter/ Linkedin/ Instagram accounts |
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Twitter/ |
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https://www.linkedin.com/in/liliana-mazur-96a57652/ |
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Instagram accounts |
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Primary focus in mechanochemical research |
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