Name

Surname

 

M. Fatima

Piedade

Institution name and department

Faculdade de Ciências da Universidade de Lisboa

Position held

 

Professor

   

Address/Country

C8, Campo Grande,1749-016 Lisboa, Portugal

E-mail

Webpage

This email address is being protected from spambots. You need JavaScript enabled to view it.

https://ciencias.ulisboa.pt/perfil/mdpiedade

Key words (up to 5)

 

Cocrystal

Polymorphism

   

Pharmaceutical

·

   

XRD

·

   

 

Areas of Research/Expertise

My background is in the areas of inorganic synthesis, solution characterization, and solid state structural analysis based on single crystal X-ray diffraction. I later developed a special interest in the fields of supramolecular chemistry, crystal engineering, hydrogen bond studies, van der Waals interactions and metal coordination. These allowed us to open new areas of research, such as the development of solid state syntheses (mechanochemistry), polymorphism and co- crystallization studies, which are currently applied to the control of behavior, stability, solubility and bioavailability of Pharmacologically Active Principles. which led to the development of new techniques and new national and international collaborations.

Collaborations for structure resolution from high quality powder diffraction data are already in place and follow real-time X-ray diffraction and FTIR reactions with data acquired at the Bessy II Synchrotron in Berlin.

5 Most representative publications related to mechanochemistry 

1.New Multicomponent Sulfadimethoxine Crystal Forms: Sulfonamides As Participants In Supramolecular Interactions

S. Domingos, A. Fernandes, M. T. Duarte, M. Fátima M. da Piedade

Crystal Growth & Design, 2016, 16, 1879−1892 DOI: 10.1021/acs.cgd.5b01320

             

 

2.  Energetics of Glycine Cocrystal or Salt Formation with Two Regioisomers: Fumaric Acid and Maleic Acid

A. O. L. Évora, C. E. S. Bernardes, M. Fatima M. Piedade, A. C. L. Conceição, M. E. Minas da Piedade

Crystal Growth and Design, 2019, 19, 5054-5064

https://doi.org/10.1021/acs.cgd.9b00379

5 Most representative publications non-related to Mechanochemistry

6.   Tautomer Selection Trough Solvent Formation: The case of 5-Hydroxynicotinic Acid.

A. Joseph, J. Rodrigues Alves, C.E.S.Bernardes, M. Fátima M. Piedade, M. E. Minas da Piedade, Crystengcomm, 2019, 21, 2220-2233. https://doi.org/10.1039/C8CE02108B

2.  Posaconazole cocrystal with superior solubility and dissolution behavior. G. Kuminek, K. Cavanagh, M. Fátima M. da Piedade, N. Rodriguez-Hornedo, Crystal Growth and Design, 2019, 19, 11, 6592-6602. https://doi.org/10.1021/acs.cgd.9b01026

3.  Polymorphism in Simvastatin: Twinning, Disorder, and Enantiotropic Phase Transitions

R. G. Simões, C..E. S. Bernardes, A. Joseph, M. Fátima M. Piedade, W. Kraus, F. Emmerling, H. P. Diogo, M. E. Minas da Piedade

Mol. Pharmaceutics, 2018, 15 (11), 5349–5360 https://doi.org/10.1021/acs.molpharmaceut.8b00818

4.   First heterobimetallic Cu(I)−dppf complexes designed for anticancer applications: synthesis, structural characterization and cytotoxicity

C. Bravo, M. P. Robalo, F. Marques, A. R. Fernandes, D. A. Sequeira, M. Fátima

M. Piedade, M. H. Garcia, M. J. Villa de Brito, T. S. Morais New Journal of Chemistry, 2019, 43, 12308-12317 https://doi.org/10.1039/C9NJ02068C

5. Eco-friendly synthesis of indo dyes mediated by a bacterial laccase

A C. Sousa, M. Fátima M. da Piedade, L. O. Martins, M. P. A. Robalo

Green Chemistry, 2016, 18, 6063-6070

https://doi.org/10.1039/C6GC02050J

Orcid ID/ Google Scholar/ Researchgate/ Scopus profiles

Orcid ID

https://orcid.org/0000-0002-5335-8810

Google Scholar

 

Researchgate

 

Scopus profiles

 

Twitter/ Linkedin/ Instagram accounts

Twitter/

 

 

Linkedin

 

Instagram accounts

 

Primary focus in mechanochemical research 

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Contact Info

  • Université de Montpellier & Institut Charles Gerhardt de Montpellier (UMR 5253)
    c/o 8, Rue de l’Ecole Normale
    34296 Montpellier, Cedex 5 (France)

  • +33 (0)4 67 14 43 10
  • This email address is being protected from spambots. You need JavaScript enabled to view it.

COST Overview

COST


EU COST is supported by the EU Framework Programme Horizon 2020.

 

 

COST Action CA18112

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