Institution name and department

Ruđer Boskovic Institute

Division of organic chemistry and biochemistry

Position held


Head of division



Bijenicka c. 54, 10000 Zagreb Croatia



This email address is being protected from spambots. You need JavaScript enabled to view it. of-Organic-Chemistry-and- Biochemistry/Laboratory-for-physical- organic-chemistry/Zaposlenici/Davor- Margetic

Key words (up to 5)


·         cycloadditions

·         heterocycles


·         green chemistry

·         organic synthesis


·         mechanochemistry




Areas of Research/Expertise 

 Physical-organic chemistry, organic synthesis, computational chemistry, reactive intermediates

5 Most representative publications related to mechanochemistry 



1.      „ Mechanochemical Friedel-Crafts acylations '', Đud, M.; Briš, A.; Jušinski, I.; Gracin. D.; Margetić, D.*, Beilst. J. Org. Chem. 2019, 15, 1313-1320. doi:10.3762/bjoc.15.130,

2.      The utilization of ball-milling in synthesis of aryl guanidines through guanidinylation and N-Boc-deprotection sequence ˝, Đud, M.; Glasovac, Z.; Margetić, D.*, Tetrahedron 2019, 75, 109-115.

3.   „ Mechanochemical catalytic transfer hydrogenation of aromatic nitro derivatives '', Portada, T.; Margetić, D.; Štrukil, V., Molecules 2018, 23(12), 3163-3180. doi:10.3390/molecules23123163 ,

4.   „ Mechanochemistry vs. solution growth: striking differences in bench stability of a cimetidine salt based on synthetic method “, Ayoub, G.; Štrukil, V.; Fábián, L.; Mottillo, C.; Bao, H.; Murata, Y.; Moores, A.; Margetić, D.; Eckert-Maksić, M.; Friščić, T., CrystEngComm 2018, 45, 7242-7247. DOI: 10.1039/C8CE01727A

5.   „ Mechanochemical N-alkylation of imides '', Briš, A.; Đud, M.; Margetić, D., Beilst. J. Org. Chem. 2017, 13, 1745-1752. DOI: 10.3762/bjoc.13.169 http://www.beilstein-

5 Most representative publications non-related to Mechanochemistry

6.   „ The photodynamic activity of 131-[2'-(2-pyridyl)ethylamine] chlorin e6 photosensitizer in human esophageal cancer ˝, Srdanović, S.; Gao, Y.-H.; Chen, D.-Y.; Yan, Y.-J.; Margetić, D.;

Chen, Z.-L., Bioorg. Med. Chem. Lett. 2018, 28(10), 1785-1791.

7.   „ A Phosphorus Bisylide: Exploring a New Class of Superbases with Two Interacting Carbon Atoms as Basicity Centers ˝, Kögel, J. F.; Margetić, D.; Xie, X.; Finger, L. H.; Sundermeyer, J., Angew. Chem. 2017, 56(11), 3090-3093. DOI: 10.1002/anie.201612446

8.         „ Insights on the auxochromic properties of guanidinium group ˝, Antol, I.; Glasovac, Z.; Margetić, D.; Crespo-Otero, R.; Barbatti, M., J. Phys. Chem. A 2016, 120(36), 7088-7100. DOI: 10.1021/acs.jpca.6b05180

9.         „ Photoinduced processes in self-assemblies of bis-porphyrinic tweezers with an axially coordinated fullerobispyridine ˝, Briš, A.; Trošelj, P.; Margetić, D.; Flamigni, L.; Ventura, B.*, ChemPlusChem 2016, 81(9), 985-994. DOI: 10.1002/cplu.201600231

10.    „ A DFT study of endocyclic allenes - unprecedentely superbasic hydrocarbons ˝, Margetić, D.; Antol, I., New J. Chem. 2016, 40, 8191-8193. DOI: 10.1039/C6NJ00623J

Orcid ID/ Google Scholar/ Researchgate/ Scopus profiles

Orcid ID

Google Scholar






Scopus profiles

Author ID: 6701410673

Twitter/ Linkedin/ Instagram accounts





Instagram accounts


Primary focus in mechanochemical research

– organic synthesis


Contact Info

  • Université de Montpellier & Institut Charles Gerhardt de Montpellier (UMR 5253)
    c/o 8, Rue de l’Ecole Normale
    34296 Montpellier, Cedex 5 (France)

  • +33 (0)4 67 14 43 10
  • This email address is being protected from spambots. You need JavaScript enabled to view it.

COST Overview


EU COST is supported by the EU Framework Programme Horizon 2020.



COST Action CA18112