Institution name and department

Dipartimento SCVSA – University of Parma

Position held





Parco delle Scienze 17A, 43124 Parma (ITALY)



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Key words (up to 5)


·       cocrystal

·       MOF


·       SC X-ray diffraction

·       XRPD


·       liquid API



Areas of Research/Expertise 

Alessia Bacchi is Professor of Chemistry at the University of Parma, and she was the President of the European Crystallographic Association (2016-2018). She authored more than 170 publications on international scientific journals, 5 book chapters, and presented more than 150 communications to national and international scientific meetings, including more than 70 oral communications presented personally, among which more than 40 have been on invitation. Her present main research interests are focused on crystal engineering of polymorphs, solvates, co-crystals, and of responsive hybrid organic/inorganic materials. Within this broad theme she developed crystalline molecular materials capable to reversibly capture and release volatile solvents in a solid/gas exchange, and proposed structural models to map the process of molecular recognition between the crystalline receptor and the volatile substrate. Recently she has focused on the design and control of crystal forms of molecular compounds, and on the stabilization inside crystalline structures (MOF and cocrystals) of liquid and volatile compounds related to human health, environment and nutrition. Along with scientific production, Alessia Bacchi is actively committed to activities of outreach and divulgation towards schools and general public, having been involved in the organization of several events and public lectures. She was the national coordinator for the activities of the International Year of Crystallography in 2014, and in the same year she curated the exhibition CRISTALLI! in Parma. In 2015 she established the Museum of Crystallography at the University of Parma, of which she is currently the Director.

5 Most representative publications related to mechanochemistry

1.      P P. Mazzeo, C Carraro, A Monica, D Capucci, P Pelagatti, F Bianchi, S Agazzi, M Careri, A Raio, M Carta, F Menicucci, M Belli, M Michelozzi, A Bacchi, Designing a Palette of Cocrystals Based on Essential Oil Constituents for Agricultural Applications, ACS Sustainable Chem. Eng. 2019, 7, 21, 17929-17940, DOI

2.      P P. Mazzeo, S Canossa, C Carraro, P Pelagatti, A Bacchi Systematic coformer contribution to cocrystal stabilization: energy and packing trends, CrystEngComm, 2020, Advance Article,

3.      A Bacchi, D Capucci, M Giannetto, M Mattarozzi, P Pelagatti, N Rodriguez-Hornedo, K Rubini, A Sala, Turning Liquid Propofol into Solid (without Freezing It): Thermodynamic Characterization of Pharmaceutical Cocrystals Built with a Liquid Drug Crystal Growth & Design 2016 16 (11), 6547-6555

5 Most representative publications non-related to Mechanochemistry 

1.      D Balestri  P.P. Mazzeo  C Carraro  N Demitri, P Pelagatti,  A Bacchi, Stepwise Evolution of Molecular Nanoaggregates Inside the Pores of a Highly Flexible Metal–Organic Framework, Angew. Chem. Int. Ed., 2019, 58, 17342-17350,

2.      A.Cruz-Cabeza, S.E. Wright, A. Bacchi, On the entropy cost of making solvates, Chem. Commun., 2020, Advance Article, DOI: 10.1039/D0CC01050B

3.      P.P. Mazzeo, C Carraro, A Arns, P Pelagatti, A Bacchi, Diversity through Similarity: A World of Polymorphs, Solid Solutions, and Cocrystals in a Vial of 4,4′-Diazopyridine, Cryst. Growth Des. 2020, 20, 2, 636-644,

4.      S Canossa, L Fornasari, N Demitri, M Mattarozzi, D Choquesillo-Lazarte, P Pelagatti , A Bacchi MOF transmetalation beyond cation substitution: defective distortion of IRMOF-9 in the spotlight, CrystEngComm, 2019,21, 827-834,

5.      A. Bacchi, P. Pelagatti, Organometallic chemistry meets crystal engineering to give responsive crystalline materials, Chem. Commun., 2016,52, 1327-1337,

Orcid ID/ Google Scholar/ Researchgate/ Scopus profiles

Orcid ID

Google Scholar




Scopus profiles


Twitter/ Linkedin/ Instagram accounts





Instagram accounts


Primary focus in mechanochemical research


Contact Info

  • Université de Montpellier & Institut Charles Gerhardt de Montpellier (UMR 5253)
    c/o 8, Rue de l’Ecole Normale
    34296 Montpellier, Cedex 5 (France)

  • +33 (0)4 67 14 43 10
  • This email address is being protected from spambots. You need JavaScript enabled to view it.

COST Overview


EU COST is supported by the EU Framework Programme Horizon 2020.



COST Action CA18112